IVIS Spectrum Whole Animal Imager

12-24-18 The IVIS will be temporarily run out of the Khurana Lab. Please contact Amin Esmaeilniakooshkghazi ( aesmaeil@Central.UH.EDU ) to make arrangements if you have mice to scan.

Features

• Adjustable field of view from 20 um (for single cells) to 22.5 cm (5 mice)
• Multimodal Imaging- can detect both fluorescent and bioluminescent reporters
• Narrow Band Excitation (415 nm-760 nm) and Emission Filters (490 nm-850 nm) enable spectral scanning over the blue to NIR wavelength region
• Can import and automatically co-register CT or MRI images to yield anatomical context

Imaging Chamber

• Light-tight imaging chamber
• Heavy-duty castors
• Integrated gas anesthesia
• Integrated fluorescence
• LED lamps for photographic images
• Heated stage to maintain optimum body temperature
• Electromagnetic door latch
• Motor-controlled stage, filter wheel, lens position, and f-stop
• Scanning laser for mouse alignment and surface topography

CCD Camera

• Back-thinned, back-illuminated grade 1 CCD provides high quantum efficiency over the entire visible to near-infrared spectrum
• 13.5 micron pixels, 2048 x 2048
• 16-bit digitizer delivers broad dynamic range
• CCD is thermoelectrically (Peltier) cooled to -90 °C , ensuring low dark current and low noise

Custom-Designed Lens

• 6-inch diameter optics, f/1– f/8 
• High-resolution - down to 20 microns
• Emission filter wheel with 24 slots